- "I had a little brother. His name was Deke. He died. Drowned, specifically. We were alone, by a river. I looked away for just a second, and… I pulled him out of the water, but I-I didn’t know CPR. All I could do was feel his pulse fade, and… stop."
- —Doc talking about Deke in A Pizza the Action
Deke DuFresne was the little brother of Frank Dufresne (Doc) who apparently drowned in a river. His brother attempted to save him but didn't know CPR and could only watch while Deke slowly died. Deke's death sparked Doc's desire to help save lives and become a medic.
- Deke is, so far, the only known relative of Doc's.